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Etomidate is a go-to induction agent in neuro anesthesia for a reason: predictable hypnosis via GABA-A receptor facilitation, decreased CMRO₂, CBF, and ICP, and excellent hemodynamic stability that helps preserve cerebral perfusion pressure. Just remember its effects on somatosensory-evoked potentials—both amplitude and latency can increase, which matters when neuromonitoring is in play. References: Barash Clinical Anesthesia, 7th Edition, pp. 489–490 Miller’s Anesthesia, 8th Edition, pp. 851–85
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