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When Benzodiazepines Do More Than Ease Anxiety Benzodiazepines can be effective short term, but daily or long-term use carries real neurologic and sleep risks. This is why duration and dosing matter. 🧠 Dependence and tolerance Regular use leads to tolerance and physical dependence. With ongoing exposure, the brain down-regulates GABA-A receptors, making the drug less effective and causing withdrawal symptoms if stopped suddenly. Clinical guidelines emphasize limiting duration because of this ri
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When Benzodiazepines Do More Than Ease Anxiety Benzodiazepines can be effective short term, but daily or long-term use carries real neurologic and sleep risks. This is why duration and dosing matter. 🧠 Dependence and tolerance Regular use leads to tolerance and physical dependence. With ongoing exposure, the brain down-regulates GABA-A receptors, making the drug less effective and causing withdrawal symptoms if stopped suddenly. Clinical guidelines emphasize limiting duration because of this ri
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