Acquired hypocomplementemia may occur in the setting of bone infections (osteomyelitis), infection of the lining of the heart (endocarditis), and cryoglobulinemia.

Individuals with a complement deficiency, including people with hereditary angioedema, can have clinical problems that are a result of the role that the specific complement protein plays in the normal …

However, in interpreting the clinical significance of hypocomplementemia, the following must be kept in mind: 1) There are numerous non-immunologic conditions that also can cause hypocomplementemia.

Hypocomplementemia is another of the altered parameters, especially in systemic vasculitis, particularly of the C1q, C2 and C4 fractions (the most common to be requested in daily practice), with C3 …

Acquired deficiencies in complement proteins are more common than inherited complement disorders. Reductions in complement secondary to acquired disease processes are usually only partial and …

Whenever there is deficiency or decreased amount of complement is observed, it is known as hypocomplementemia. In this condition, a part or component of complement is reduced in amount.

The meaning of HYPOCOMPLEMENTEMIA is an abnormal deficiency of complement in the blood.