The Hughes Fire near Castaic, California, has burned over 5,000 acres, prompting evacuations and school closures.

A rare Particularly Dangerous Situation warning has been issued for Southern California as a powerful and potentially damaging Santa Ana wind event​ is expected.

The Los Angeles haven’t spread in nearly a week, but the return of the Santa Ana winds to full strength could cause problems.

"A strong Santa Ana Wind event is expected to develop Monday and last through at least Tuesday," the National Weather Service said.

The Santa Ana winds fanning wildfires that have killed at least 25 people in Southern California and destroyed more than 10,000 houses, businesses and other structures in Greater Los Angeles are flaring up again.

The Santa Anas are expected to be most powerful Monday night into Tuesday. Fire services across the region say they are ready.

After a much quieter weekend, Southern California is experiencing a major shift in the weather pattern. The winds will peak Monday evening and overnight but extend into Tuesday morning.

A wind-driven wildfire charred dozens of acres in the sparsely developed northeastern reaches of San Diego County, damaging structures and forcing pre-dawn evacuations before crews could gain the upper hand on the flames Wednesday.

Santa Ana winds continued challenging firefighters on the Palisades and Eaton fires, but containment inched forward along the coast, and debris cleanup was underway in both burn scars ahead of possible rain coming over the weekend, authorities said.

The Palisades and Eaton wildfires also continue burning in the Los Angeles area, leaving parts of Southern California with devastating fire damage.

After weeks of dealing with fires, Southern California will soon have to brace for possible weekend storms and potential mudslides.