In the early days of President Donald Trump's second term, Alaska Sen. Lisa Murkowski has openly challenged or rebuked him at least three times — stunning for a congressional Republican who has faced his wrath before and yet remains unbowed by pressure to embrace his agenda.

Lisa Murkowski, a frequent thorn in the U.S. president’s side, says the Arctic island is “open for business, but not for sale.”

President Donald Trump has kicked off his second term with a flurry of executive actions on immigration, the economy, DEI and more.

Sen. Lisa Murkowski (R-AK) has a wake-up call for President Donald Trump over his ongoing obsession with acquiring Greenland as part of the United States: they're an "ally, not an asset." In a joint statement with Danish MP Aaja Chemnitz,

We shouldn’t expect McConnell to be the next John McCain or Mitt Romney, but his vote Friday against Pete Hegseth previewed some fascinating dynamics ahead.

At the White House, President Donald Trump said he was surprised that two senators have publicly said they'll vote against his nominee to lead the Defense Department.

A defining duo of the first Donald Trump administration is back.

Hours after Pete Hegseth cleared a major procedural hurdle in the Senate, President Trump suggested his embattled nominee may not ultimately be confirmed.

Lisa Murkowski announced Thursday that she will vote against confirming Pete Hegseth to lead Pentagon, becoming the first Republican to oppose one of President Donald Trump’s Cabinet picks.

The 44-year-old veteran and former Fox News host was sworn into office Saturday after facing allegations of sexual misconduct, misogynistic and racist comments, and mismanaged finances at two organizations.

U.S. Sen Lisa Murkowski was alone in stridently opposing Trump’s blanket pardon for Jan. 6 defendants, and his order to rename Denali as Mount McKinley.

President Donald Trump said he was “surprised” that Republican Sens. Susan Collins (Maine) and Lisa Murkowski (Alaska) voted to oppose Pete Hegseth’s defense secretary nomination.