Assessing which genes are active in a given tissue at a specific time, and determining the relative degree of gene activity are essential steps in understanding how the genome as a whole functions ...

Cells don’t operate in isolation. They constitute and reside in highly complex, interconnected tissue systems. They exert biological influence on their surroundings and are functionally differentiated ...

Massively parallel strand-specific sequencing of RNA (ssRNA-seq) has emerged as a powerful tool for profiling complex transcriptomes. However, many current methods for ssRNA-seq suffer from the ...

Geneticists subject to late-night bouts of inspiration generally have to write down their good ideas. It's not as if you could just walk across the room, get the gene you need for your experiment, and ...

What is an RNA sequencing library? In all RNA-seq experiments, a library of cDNA fragments attached to adapters must be synthesized in order for sequencing to be successful. How do you prepare an RNA ...

As the SARS-CoV-2 virus continues to mutate, rapid sequencing of COVID-19-positive samples is more critical than ever. Next-generation sequencing (NGS) is the best technology for identifying both ...