Translation initiation in eukaryotes is a highly regulated process and requires the interplay of several translation initiation factors [1, 2]. It begins with delivery of Met-tRNA i Met to the ...

A study of molecular structure reveals how a small chemical change can make a big difference to function in a cell’s response to stress ...

This is a preview. Log in through your library . Abstract A core event in the integrated stress response, an adaptive pathway common to all eukaryotic cells in response to various stress stimuli, is ...

As axonal mitochondria are lost, changes in the subunits of eIF2 are seen which hamper translation and autophagy and cause the accumulation of proteins in cells. Tokyo, Japan – Researchers from Tokyo ...

Scientists have revealed an entirely new mechanism through which hemoglobin gene expression is regulated by stress. Our ability to breathe oxygen is critical to our survival. This process is mediated ...