There are different types of leukemia, depending on the type of WBC they arise from and on the stages that these cells pass through as they mature. AML is categorized as a diverse and heterogenous ...
New developments in the complex and rapidly changing world of acute myeloid leukemia (AML) promise to improve health outcomes for people with the disease. They include: Advances in diagnostics ...
Panelists discuss how current risk stratification systems, particularly the European Leukemia Net 2022 classification for intensive therapy and the 2024 classification for lower intensity treatments, ...
•Genomic characterization determines diagnosis, classification, and prognostication of the myeloid malignancies myelodysplastic syndrome (MDS) and AML. •Recognizing genetic lesions as invariable ...
—Classifying myelodysplastic syndrome and secondary acute myeloid leukemia by genetic mutations rather than strictly by blast count may allow more patients to be eligible for AML and MDS clinical ...
Table 1. Novel prognostic markers in acute myeloid leukemia. AML: Acute myeloid leukemia; APL: Acute promyelocytic leukemia; CBF: Core-binding factor; CEBPA-DM: CCAAT enhancer-binding protein-α with ...
NPM1-mutated AML prognosis was refined using a new genetic model integrating co-mutations, improving risk classification and ...
Leukemias are classified according to their acute and chronic progress as well as according to their lymphoid or myeloid cell origins. Acute myeloid leukemia is further classified into subtypes. Most ...
Recent studies have provided a detailed census of genes that are mutated in acute myeloid leukemia (AML). Our next challenge is to understand how this genetic diversity defines the pathophysiology of ...
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