Research co-led by King's College London and Sidra Medicine, Qatar, has produced the most detailed map to date of large-scale ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

Enzymes that cut DNA at specific sites are called endonucleases; these enzymes play many roles in genomic replication, fidelity, and defense. The initial discovery of restriction endonucleases in the ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed. The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a ...

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a ...

They were hardly modest, these two brash young scientists who in 1953 declared to patrons of the Eagle Pub in Cambridge, England, that they had "found the secret of life." But James Watson and Francis ...

In the middle of the 20th century, accumulating data suggested that DNA carries life’s genetic information. Biochemists around the world raced to determine its structure. The competition led to some ...

DNA nanotechnology has become an intense research field, with hundreds of research labs engaged in it, based on the idea that DNA can be used as a programmable structural material for the creation of ...

On the left side, in vitro preassembled DNA circuits are delivered into living cells. Alternatively, on the right side, RNA pregates are autonomously transcribed from the chromosome or plasmids to be ...