Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

Using machine learning to guide microscopes could reveal greater insights into the brain's connectome and deepen our ...

A decade ago, the Nobel Prize in Chemistry was awarded to a trio of researchers for the development of super-resolved fluorescence microscopy. The announcement at the time stated that the researchers’ ...

Researchers have developed a compact handheld imaging probe that could expand the clinical and research use of photoacoustic ...

SIMIP enables high-resolution images rich in both chemical and spatial information. A quantum cascade laser (QCL) excites molecular vibrations while a spatial light modulator (SLM) generates striped ...

Computational fluorescence microscopy (CFM) requires accurate point spread function (PSF) characterization for high-quality ...

What is High-Resolution Transmission Electron Microscopy (HRTEM)? High-resolution transmission electron microscopy (HRTEM) is an advanced imaging technique that enables the direct visualization of ...

Microscopes have long been scientists’ eyes into the unseen, revealing everything from bustling cells to viruses and nanoscale structures. However, even the most powerful optical microscopes have been ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

What is the Diffraction Limit? The diffraction limit is a fundamental barrier in optical microscopy that sets the minimum size of features that can be resolved using conventional light microscopes. It ...