DNA Repair Pathways in Clinical Practice: Lessons From Pediatric Cancer Susceptibility Syndromes. If you have the appropriate software installed, you can download article citation data to the citation ...

A study has uncovered new findings about a DNA repair pathway called nucleotide excision repair and its role in the development of cancer. The paper also details how this defective pathway could be ...

It is important that we learn how to exploit DNA damage repair deficiencies to treat cancer help patients in control their disease. explained Hatem Soliman, MD, medical director, Clinical Trials ...

A research team has successfully identified a novel DNA damage repair pathway in human cells. This study is the first to discover that proteins present in the nuclear membrane of cells directly ...

Scientists have discovered a molecular pathway that works through the immune system to regenerate damaged kidney tissues and may lead to new therapies for repairing injury in other organs. The study ...

Several cancer chemotherapy drugs work by producing excessive DNA damage that causes cell death directly or following DNA replication. Survival is promoted through repair of these lesions by a number ...

The human immunodeficiency virus, the cause of AIDS, makes use of the base excision repair pathway when inserting its DNA into the host-cell genome, according to a new study. The research shows that ...

DNA repair pathways exist to correct molecular damage caused by internal and external factors. However, any damage to these pathways can result in the creation of tumors and specific types of cancers.

A new study in fruit flies describes how an animal’s gut reacts differently to beneficial microbes versus harmful pathogens. A pathway known for repairing damaged genetic material, called the ...