Artificial intelligence (AI) is transforming how scientists understand proteins—these are working molecules that drive nearly every process in the human body, from cell growth and immune defense to ...

Researchers found that paired pathogenic variants can restore protein function rather than make it worse. This phenomenon ...

Age-related changes in protein tagging and degradation may help explain how the brain declines over time and why diet can ...

In the early 1990s, protein biologists invested in solving a challenge that had riddled them for decades. The protein folding problem centered on the idea that biologists should be able to predict the ...

Targeted protein degradation (TPD) approaches including PROTAC and molecular glue have revolutionized drug discovery. However, in part due to complication of the ubiquitination and related ...

Proteins are essential macromolecules that play a crucial role in virtually all biological processes. They are the building blocks of life, performing a wide range of functions within organisms, from ...

Astronomers use the term dark energy to refer to energy in the universe that is unaccounted for by ordinary matter but necessary to explain cosmology. Astronomy, however, isn't the only field with ...

From molecular chaperones to mitochondrial failure, discover how heat reshapes the human transcriptome and drives the biological cascade that links rising temperatures to organ injury and public ...