A new LMU study shows how proteins function reliably even without a stable 3D structure—and the crucial importance not only of short sequence motifs, but also of chemical characteristics.

Proteins are the end products of the decoding process that starts with the information in cellular DNA. As workhorses of the cell, proteins compose structural and motor elements in the cell, and they ...

Michael Martynowycz, PhD, assistant professor of structural biology at the Jacobs School of Medicine and Biomedical Sciences, recently described a new technique for solving protein structures in a rec ...

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only of short sequence motifs, but also of the chemical characteristics.

Recent advances in computational biology have revolutionised the field of protein structure and function prediction. Traditionally, determining the three‐dimensional architecture of a protein from its ...

In genetics, one harmful variant can be enough to cause disease—but two can make it far more severe. One notable example is KJ, an infant diagnosed with a rare urea cycle disorder with a grim ...

Many proteins have a complex architecture that enables biological functions. Molecules can bind to specific sites on a protein and alter its function. A team at HZB has now investigated the Nsp1 ...

David Baker, Demis Hassabis and John M. Jumper shared the Nobel Prize in Chemistry on Wednesday for their work on protein structure. Atila Altuntas / Anadolu via Getty Images On Wednesday morning, ...

This fully updated volume explores a wide array of new and state-of-the-art tools and resources for protein function prediction. Beginning with in-depth overviews of essential underlying computational ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

A protein that is a key modulator of fat, glucose and cholesterol levels in the body usually works in tandem with another protein, but new research shows it can also work with an unexpected ...

Advanced proteomics and AI reveal blood protein changes, offering insights into early Alzheimer's detection and differentiation from mild cognitive impairment.