Mitochondria have critical cellular functions including energy mobilization, calcium regulation, metabolite production and redox homeostasis 1,2. However, mitochondrial proteins are challenged by ...

Cilia are antennae-like vestigial organelles that project from the outside of virtually all eukaryotic cells. Primary cilia are typically non-motile, sense extracellular signals, and act as regulators ...

A significant step forward in protein design from Generate Biomedicines, Massachusetts, has developed an AI that can generate feasible protein structures and predict the potential functionality of the ...

In genetics, one harmful variant can be enough to cause disease—but two can make it far more severe. One notable example is KJ, an infant diagnosed with a rare urea cycle disorder with a grim ...

Proteomics is the large-scale study of proteins, particularly their structures and functions. It involves the systematic identification, quantification, and analysis of the entire protein complement ...

Researchers created a DIA-MS atlas of 13,609 proteins across 2,856 samples from fetal, healthy adult, paired non-tumor, and ...