Terc-53 functions as a molecular scaffold bringing together Hmmr and Trim25, accelerating Hmmr’s ubiquitination-mediated degradation, which consequently leads to neuroinflammation and cognition ...
When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...
A research team led by scientists at Columbia’s Zuckerman Institute used techniques including single cell genomics, to describe a previously undetected RNA-mediated mechanism in mice that could ...
RIKEN researchers have discovered how an enzyme modifies gene expression by targeting certain stretches of messenger RNA ...
Bayer executives were keen to stress to Fierce this summer that the German pharma giant’s appetite for dealmaking hasn’t been curbed by a groupwide restructuring. Its latest cancer-focused ...
RNA-binding proteins use a dual binding mechanism involving zinc finger (ZnF) domains and intrinsically disordered regions (IDR), reports a new study from Institute of Science Tokyo, Japan. Using ...
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