The neuromuscular junction - where nerves and muscle fibers meet - is an essential synapse for muscle contraction and movement. Improper function of these junctions can lead to the development of ...

James F. Howard Jr, MD, professor of neurology at the University of North Carolina at Chapel Hill, explains how nerve and muscle signaling in the neuromuscular junction go awry in myasthenia gravis.

Neuromuscular diseases are caused by problems in the way muscle cells, motor neurons, and peripheral cells interact. Researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz ...

The muscle transmembrane protein Vangl2 helps organize the development and maintenance of connections between muscles and motor neurons, a study concludes. A skeletal muscle isn’t much use without a ...

New data suggest motor function improves with amifampridine. New phase 2 data for the spinal muscular atrophy (SMA) therapy amifampridine (Ruzurgi) suggests the drug is safe and effective at improving ...

The neuromuscular junction (NMJ) is a specialised synapse responsible for translating neuronal signals into muscle contractions, forming the basis of voluntary movement and postural control. Integral ...

Does Alzheimer’s start in the muscles? Research reveals that motor neuron mutations disrupt the neuromuscular junction ...

Researchers report that certain movement-related symptoms of Alzheimer’s disease may originate in the peripheral nervous ...

Frog neuromuscular junction fly-through. Shown in red is a large muscle fiber (diameter 50 micrometers) that is innervated by a myelinated axon colored in white. The interface between muscle and axon ...