Matthew Perry found fame fast when he was cast in Friends, which premiered 31 years ago this September. He auditioned for the show. When he read the script for the first time, he thought, “My God!

For a die-hard fan, it may seem like all of Hollywood's biggest stars eventually made their way onto hit sitcom Friends.

During its decade-long run, "Friends" boasted a litany of guest stars, like Julia Roberts, George Clooney, Brad Pitt, and Tom Selleck. For 10 episodes across Seasons 2, 3, and 6, Selleck played Dr.

Perry opened up to PEOPLE in September 1995 about how the show, which had just began airing its second season, had already changed his life Alice S. Hall/NBCU Photo Bank/NBCUniversal via Getty; PEOPLE ...