Liquid-liquid phase separation (LLPS) and crystallization are intertwined phenomena of considerable importance in both fundamental research and industrial applications, particularly in the ...
Multivalent interactions between biological molecules result in the formation of biomolecular condensates, a phenomenon known as Liquid–liquid phase separation (LLPS). Biomolecular condensates have ...
Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets ...
Chemidroplet is a chemical tool, that fused the BTB-containing domain to the multivalent DNA binding domain (DBD) and intrinsically disordered regions (IDRs) to readily control the LLPS of these ...
LLPS as a rising molecular entity in the cytoplasm regulates diseases progression via a variety of ways. For example, the relationship between LLPS and cancer can be summarized into six aspects: gene ...