Morning Overview on MSN
Engineered lipid nanoparticles reprogram immune metabolism to boost mRNA
Researchers are redesigning lipid nanoparticles to do more than shuttle mRNA into cells, with preclinical studies suggesting ...
The most common side effects of mRNA vaccines like the COVID-19 shot are well known: soreness, mild fever, and general malaise. Those symptoms, which typically resolve within days, are the natural ...
Morning Overview on MSN
Prodrug lipid nanoparticle delivers IDO inhibitor and mRNA to fight tumors
Engineers at the University of Pennsylvania have built a lipid nanoparticle that chemically fuses an IDO-pathway inhibitor with the very lipids that carry IL-12 mRNA into tumors, creating a single ...
Researchers at the University of Toronto have developed LUMI-lab, an AI-enabled self-driving laboratory that has identified brominated lipid tails as a potent and previously unrecognised enhancer ...
Using artificial intelligence (AI), researchers headed by a team at Massachusetts Institute of Technology (MIT) have come up with a new way to design nanoparticles that can more efficiently deliver ...
A review maps high throughput strategies that link automation, microfluidics, and barcoding into a unified pipeline, enabling faster, more predictive lipid nanoparticle development for genetic ...
“We’ve never had such an in-depth map of the CD1 lipidome available,” said Patricia Barral, an immunologist at King’s College London who was not involved with the work. “It will enable us to start ...
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