The most common side effects of mRNA vaccines like the COVID-19 shot are well known: soreness, mild fever, and general ...
Engineers at the University of Pennsylvania have built a lipid nanoparticle that chemically fuses an IDO-pathway inhibitor with the very lipids that carry IL-12 mRNA into tumors, creating a single ...
Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues. A team led by ...
Researchers at the University of Toronto have developed LUMI-lab, an AI-enabled self-driving laboratory that has identified brominated lipid tails as a potent and previously unrecognised enhancer ...
Using artificial intelligence (AI), researchers headed by a team at Massachusetts Institute of Technology (MIT) have come up with a new way to design nanoparticles that can more efficiently deliver ...
“We’ve never had such an in-depth map of the CD1 lipidome available,” said Patricia Barral, an immunologist at King’s College London who was not involved with the work. “It will enable us to start ...
To test whether AT2‑derived lipids are required for metastasis, the researchers selectively deleted Fasn in AT2 cells.
Researchers are redesigning lipid nanoparticles to do more than shuttle mRNA into cells, with preclinical studies suggesting ...