During animal development, cells divide and arrange themselves in a coordinated way, eventually forming the embryo. The cells communicate with each other during this process through cell-surface ...

Cell membrane receptors are important therapeutic targets in many diseases, including cancer. The efficacy of targeted protein degraders of intracellular proteins, such as proteolysis-targeting ...

Recently these monocyte-derived alveolar macrophages, or Mo-AMs, were identified as key drivers of lung fibrosis disease progression. However, the mechanisms of their pro-fibrotic behavior and ...

Triggering receptors expressed on myeloid cells (TREMs) are a cell surface receptor family found on granulocytes, monocytes, macrophages, and dendritic cells—as well as other myeloid cells in general.

New research combines two powerful imaging techniques to study the complete structure of a common aGPCR, including how its long and complex extracellular region interacts with the transmembrane region ...

Viruses attack nearly every living organism on Earth. To do so, they rely on highly specialized proteins that recognize and ...