Immune system activation and activity is regulated through stimulatory or inhibitory ligand-receptor interactions collectively termed immune checkpoints. 1 Stimulatory interactions give the immune ...

Hepatocellular carcinoma (HCC) stands as the dominant form of liver cancer, ranking as the fourth leading cause of cancer-related deaths globally. Often diagnosed at advanced stages, the therapeutic ...

Immunotherapy has revolutionized cancer treatment, with immune checkpoint inhibitors (ICIs) playing a pivotal role. However, current ICIs, primarily monoclonal antibodies, face significant challenges ...

The integration of single-cell and spatial transcriptomics with advanced metabolic profiling tools has revolutionized the ...

Immune checkpoint inhibitors (ICIs) are a form of immunotherapy that activates anti-tumor immune cells. In the context of ...

MSI-H mCRC patients receiving ICIs had significantly improved OS compared to chemotherapy, with a 63% improvement in survival. MSS patients with high albumin levels or recent antibiotic use also ...

In a study published in February 2026 in JCO Oncology Practice, investigators from Sweden report that influenza vaccination during treatment with immune checkpoint inhibitors was associated with ...

Immune checkpoint inhibitors and other immunotherapies/ cancer vaccines have revolutionised the oncology landscape, offering durable responses in cancers ...

Please provide your email address to receive an email when new articles are posted on . Chronic cutaneous immune-related adverse events often persist more than a year after discontinuation of immune ...

An international team of UK and US scientists has discovered that the activity of macrophages—a type of white blood cell that engulf pathogens and cancer cells—can be used to predict whether or not a ...