Structural variants (SVs) are alterations in the DNA sequence that involve large-scale changes, typically longer than 50 base pairs. Advances in long-read sequencing have significantly increased ...

Completed in 2003, the Human Genome Project gave us the first sequence of the human genome, albeit based on DNA from a small handful of people. Building upon its success, the 1000 Genomes Project was ...

A team led by researchers at UCLA and the University of Pennsylvania has produced a first-of-its kind catalog of gene-isoform variation in the developing human brain. This novel dataset provides ...

Most research in human genetics has historically focused on people of European ancestries—a long-standing bias that may limit the accuracy of scientific predictions for people from other populations.

Putting aside the risk of an early grave by accident or injury, your genes may have a much greater impact on your lifespan ...

An international research collaboration has shed new light on how DNA sequence variation can influence gene activity in the developing human brain. The team, which was led by researchers at the ...

Veronica Paulus is a former STAT intern supported by the Harvard University Institute of Politics. Complex regions of the human genome remained uncharted, even after researchers sequenced the genome ...

The headline figure of lifespan being around “50% heritable” risks being misunderstood as meaning genes determine half of a ...

In the ongoing effort to determine just how much of who we are is preordained by our genetic code, heritability, a statistical measurement of how much variation in a trait can be attributed to genetic ...