The use of acidic MPAs (pH 2–4) is the default in pharmaceutical testing because they suppress silanol ionization (from Si-OH to Si-O -) and improve peak shape for basic drugs. However, highly ...
From our June 15 Issue: HPLC’s Discriminating Power Quietly Resolves Madding Mixtures and Methodically Sequesters Compounds When Waters introduced the first commercial high-performance liquid ...