The new CRISPR platform, called ΨDNA, reprograms Cas12 nucleases to recognize and act on RNA using a DNA-based guide scaffold ...

Columbia University researchers have built a deep-learning model that predicts how CRISPR guide RNAs will behave when targeting messenger RNA inside human cells, a capability that could reshape how ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...

On the left are three forms of the same RNA molecule, which is stabilised into a single form (on the right) by mitoxantrone. Ribonucleic acids (RNAs) serve as messengers between DNA and protein ...

Ribonucleic acid, commonly known as RNA, is involved in many biological functions, and some, including gene silencing, are utilized to cure diseases. RNA has recently gained attention as a promising ...

Researchers from A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a new method to study individual RNA ...

The National Institutes of Health (NIH) has partnered with the U.S. National Science Foundation (NSF) to provide approximately $15.4 million over three years for research into the structures, ...

While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and ...