When the Ebola virus infects a host cell, the first thing it does is attach itself to the cell using a glycoprotein. A newly obtained structure of that glycoprotein—the highest resolution one to ...

Duke Human Vaccine Institute (DHVI) investigators used a technique called time-resolved, temperature-jump (TR, T-Jump) small-angle x-ray scattering (SAXS) to capture the spectacularly brief moment ...

Data shows how antibodies bind to V1/V2 domain. Scientists report on the structure of the HIV-1 gp120 glycoprotein’s V1/V2 domain and how a broadly neutralizing antibody binds to the structure and ...

Filoviruses get their name from the Latin word "filum," meaning thread—a reference to their long, filamentous shape. This ...

EBV, a human herpesvirus, is a DNA tumor virus that primarily infects B cells. EBV infection is associated with a variety of human cancers, including Burkitt lymphoma, Hodgkin disease, nasopharyngeal ...

Since the coronavirus disease 2019 (COVID-19) pandemic spread around the world, researchers across the globe have been analyzing severe acute respiratory syndrome 2 (SARS-CoV-2), as well as similar ...

Spike glycoprotein structure of SARS-CoV, the coronavirus causing the 2002 outbreak. When linoleic acid is bound, the structure is locked in a non-infectious form. The cryo-EM density, calculated by ...

Scientists plan to use their new map of the Lassa virus surface glycoprotein to design a much-needed vaccine. A new study from scientists at La Jolla Institute for Immunology (LJI) gives researchers a ...

video: This spinning blue shape is the outer shell (glycoprotein) that shields lymphocytic choriomeningitis virus (LCMV) from immune system attack. And yet new research shows that an antibody (grey) ...

A new study from scientists at La Jolla Institute for Immunology (LJI) gives researchers a guide to neutralizing Lassa virus using a trio of rare antibodies isolated from survivors of Lassa virus ...

Researchers have mapped the conformational changes that occur in a protein 'notorious' for pumping chemotherapeutic drugs out of cancer cells and blocking medications from reaching the central nervous ...