MHC class II molecules are central to the adaptive immune response, serving as the means by which antigen-presenting cells, notably dendritic cells, display processed peptides to CD4+ T cells. This ...
The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...
EPFL researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a ...
Cancer immunotherapy transforms a patient’s immune cells into a “search‑and‑destroy” force against tumors. But many cancers learn to camouflage themselves from dendritic cells—the immune system’s ...
The immune system provides constant surveillance for the body, aiming to spot and eliminate disease-causing microbes or cancerous cells. But tumor cells develop many features that help them hide from ...
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Blocking retinoic acid pathway improves dendritic cell anti-tumor function
Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by ...
New evidence shows that human M cells act as fully fledged antigen-presenting cells, processing and presenting gluten peptides through a dendritic cell-like pathway that may shape early coeliac ...
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