The DNA double helix is composed of two DNA molecules whose sequences are complementary to each other. The stability of the duplex can be fine-tuned in the lab by controlling the amount and location ...
In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...
As nucleic acid sequencing has become dazzlingly fast, accurate, and affordable, sequencing a whole genome has gone from a trumpeted accomplishment to another day at the office. Now, metagenomic ...