Clinical research has always been the backbone of medical progress, providing the data and insights needed to develop new treatments, improve patient outcomes, and advance public health. Yet, the ...

In this video interview, Marc Buyse, ScD, founder and CEO of IDDI, makes the case for generalized pairwise comparisons and the win ratio as transformative approaches to trial analysis that incorporate ...

In 2022, Rafael Nadal approached the baseline and began horizontally abducting his right arm to loft a tennis ball approximately 5 feet. He abruptly contacted the inferolateral aspect of the tennis ...

In a new draft guidance issued on January 14, 2026, the FDA discussed the use of a modern statistical methodology in clinical trials designed to show the effectiveness of a new drug. The guidance, ...

The FDA has released a draft guidance outlining how drug developers can validate new approach methodologies (NAMs) as alternatives to animal testing in preclinical drug development. The guidance, ...

Researchers have developed a method to accurately detect viruses from clinical next-generation sequencing and describe novel associations between specific tumors and viruses that warrant further ...

The COVID-19 pandemic accelerated the adoption of community-based (decentralized) clinical trials, telemedicine, remote monitoring of trial participants, and other novel clinical research methods that ...

Unfortunately, this book can't be printed from the OpenBook. If you need to print pages from this book, we recommend downloading it as a PDF. Visit NAP.edu/10766 to get more information about this ...

Please provide your email address to receive an email when new articles are posted on . Unlike the current clinical method for measuring visual midline shifts, the visual midline gauge provides ...