Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or even no symptoms. Researchers in previous studies have discovered one reason why: cells ...

Improvements in public health have allowed humankind to survive to older ages than ever before, but, for many people, these ...

The immune system provides an integral defense against cancer growth and progression. Activating an anti-tumor immune response relies on several biological steps that can ultimately result in the ...

A new study from Whitehead Institute Member Jonathan Weissman reveals how cells may activate a compensation system that can, in some cases, reduce the effects of potentially harmful genetic mutations.

When a cell divides, it performs a feat of microscopic choreography—duplicating its DNA and depositing it into two new cells.

Goal Is to Optimize Growth Conditions for Sustaining High Productivity in Culture Maintaining cell lines in culture, under optimal growth conditions, is essential for production of many biological ...

At the 2024 annual meeting of the International Society for Cell & Gene Therapy (ISCT) in Vancouver, Canada, Hélio Tomás, PhD, senior research associate at the Instituto de Biologia Experimental e ...

A cell's identity is based on the genes it expresses, and scientists have been studying gene expression mechanisms for many years. But the process involves molecules that are too small to see, until ...

Scientists have found how human cells distribute and maintain their cholesterol levels, aiding in research in neurodegenerative diseases such as Alzheimer's disease, as well as cardiovascular diseases ...

As we age, our cells don’t just wear down—they reorganize. Researchers found that cells actively remodel a key structure called the endoplasmic reticulum, reducing protein-producing regions while ...