For doctors trying to treat people who have symptoms that have no clear cause, gene-sequencing technologies might help in pointing them to a diagnosis. But the vast amount of data generated can make ...

In the field of biomedical research and genomics, the advancement of bioinformatics technologies and tools is opening new frontiers in the understanding of diseases and their diagnosis and treatment.

A new bioinformatics platform called Empowering the Development of Genomics Expertise (EDGE) will help democratize the genomics revolution by allowing users with limited bioinformatics expertise to ...

Many proteins are capable of spontaneously rearranging themselves within cells to form molecular condensates—membraneless intracellular structures formed by one or multiple proteins—through a process ...

We are living in an era where biology has become synonymous with big data due to the ever-increasing amount of data being generated by technologies such as next-generation sequencing. Bioinformatics ...

Clinical testing with next generation sequencing requires a complex bioinformatics pipeline to process raw DNA sequence into interpretable variants for medical reporting. With sequencing costs ...

The integrative analysis of diverse data types with multiple software tools remains an enormous challenge for many biologists. There is an ever-growing gap between the need to use various analysis and ...

The Lazypipe series is a collection of bioinformatics pipelines developed by our research group to enhance the discovery and analysis of viruses from metagenomic next-generation sequencing (mNGS) data ...

Melyssa Minto (left) is an omics researcher and bioinformatics scientist at RTI International (NC, USA), where she uses multiomic data to understand how the central dogma of biology – the way genetic ...