The cellular abundance of transcription factors (TFs) is an important determinant of their regulatory activities. Deriving TF copy numbers is therefore crucial to understanding how these proteins ...

Researchers from Critical Analytics for Manufacturing Personalized-Medicine (CAMP), an Interdisciplinary Research Group (IRG) at the Singapore-MIT Alliance for Research and Technology (SMART), MIT's ...

Whitehead Institute scientists have developed a method to quickly isolate and systematically measure metabolite concentrations within the cellular organelles known as mitochondria, often referred to ...

In a recent medRxiv* preprint manuscript, researchers from Singapore and the United States report the development of a digital CRISPR method for the sensitive, specific, and rapid detection of viral ...

A team at NDORMS has developed a new approach to significantly improve the accuracy of RNA sequencing. They have pinpointed the primary source of inaccurate quantification in both short and long-read ...

QPrESTs consists of 50-150 amino acids identical to a part of the corresponding human protein. They are produced recombinantly in the presence of stable isotope-labeled (i.e. heavy) amino acids to ...

The QX700™ family of Droplet Digital™ PCR (ddPCR™) Systems brings high-sensitivity absolute quantification and advanced multiplexing together in a single, scalable platform. Unlike real-time qPCR, ...

Mass spectrometry just isn't inherently quantitative because of differences within the ionization efficiency and/or detectability of the many peptides in a given sample, which has sparked the ...

Proteomics is a research field focusing on the large-scale study of proteins in biological contexts. The goal is to describe various biological questions related to aging, drug treatment, disease, and ...