A 3D model accurately mimicking the Blood-Brain Barrier (BBB) in a laboratory environment has been successfully developed by research teams led by Professor Jinah Jang from the Departments of ...

An international research team has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin—DNA and proteins—plays a ...

A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells and the vasculature into a single culture. Grown ...

BigBrain, a 3D digital reconstruction of a human brain, provides a first-ever high resolution view of the inner workings of the human brain that could lead to better understanding of how we think, ...

Researchers have crossed a threshold that once belonged squarely to science fiction: they have built working models of brains, both in silicon and in living tissue, that can learn, adapt, and even ...

Cerebrovascular diseases such as atherosclerosis and stroke remain a major cause of morbidity and mortality worldwide. A common feature of these diseases is vascular stenosis, i.e., the narrowing of ...

Johns Hopkins University researchers have grown a novel whole-brain organoid, complete with neural tissues and rudimentary blood vessels—an advance that could usher in a new era of research into ...

In a little over ten years, organoid models—miniature, lab-grown clusters of cells that imitate real organs—have transformed how we study human development and disease while accelerating drug ...

Scientists at Johns Hopkins have grown a first-of-its-kind organoid mimicking an entire human brain, complete with rudimentary blood vessels and neural activity. This new "multi-region brain organoid" ...