The Arizona Cardinals close out the season in Week 18 at home facing the San Francisco 49ers for the second time. The Cardinals won the first meeting in Week 5 in Santa Clara 24-23 on a last-minute field goal by kicker Chad Ryland,

See what Kyle Shanahan, Joshua Dobbs, Jonathan Gannon and Kyler Murray had to say following the Week 18 contest.

The San Francisco 49ers (6-10) are 4.5-point underdogs as they try to break their three-game losing streak in a matchup against the Arizona Cardinals (7-9) on Sunday, January 5, 2025 at State Farm

The Arizona Cardinals play their final game of the season Sunday afternoon at State Farm Stadium, taking on the San Francisco 49ers for the second time. To prepare for the game, cohost Seth Cox and I

See who's in and who's out for the Week 18 matchup between the Arizona Cardinals and San Francisco 49ers on January 5, 2025.

The Arizona Cardinals face the San Francisco 49ers in Week 18 at State Farm Stadium to close out the season. They want to finish with a win. They are down to backup and fourth-string tackles, and Michael Carter will start at running back. But the 49ers will have Josh Dobbs at quarterback, a rookie at running back and a depleted offensive line.

What's the San Francisco 49ers vs Arizona Cardinals score? Follow our live updates for latest news, highlights, analysis from NFL Week 18 game.

With starting QB Brock Purdy working through an elbow injury he sustained in the 49ers’ Week 17 loss to the Detroit Lions, Joshua Dobbs will get the start under center according to head coach Kyle Shanahan. Brandon Allen, who started the team’s Week 12 game in Green Bay, will be the backup.

It’s 49ers vs. Cardinals in Week 18 of the 2024 NFL season. Here’s how to watch, including time, channel, TV schedule and streaming info.